Hilltop Label

National Center for Biotechnology Information National Center for Biotechnology Information Bias was reduced in an open-label trial through the removal of ... Bias was reduced in an open-label trial through the removal of subjective elements from the outcome definition Modifying the outcome definition to exclude subjective elements substantially reduced bias. This may be a useful strategy for reducing bias in trials that cannot blind outcome assessment. PDF Blinding Sponsors for Open Label Studies: Challenges and Solutions - MWSUG Even for open label studies, it's still desirable blind the study sponsor to reduce potential bias due to the sponsor knowing the treatment level aggregated data while the study is ongoing. The practice helps increase credibility of study results and thus should be followed, particularly for registration studies. In open label studies, in ... Open-label study bias